Colorectal cancer. Early research suggests that taking a specific turmeric product containing turmeric extract and Javanese turmeric extract (P54FP, Phytopharm plc., Godmanchester, United Kingdom) might stabilize some measures of colon cancer. There is also early evidence that taking curcumin, a chemical found in turmeric, daily for 30 days can reduce the number of precancerous glands in the colon of people at high risk of cancer.
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Curcumin’s anti-inflammatory, antioxidant, and antimicrobial properties make it a health-promoting powerhouse. While curcumin is not absorbed that well into the bloodstream, consuming it with black pepper enhances absorption, thanks to a substance in the pepper called piperine. One of my favorite remedies I learned at the clinic was a cold-fighting tea with ginger and black pepper. Add one teaspoon of turmeric to 12 ounces of water and bring to a boil. Take the water off the heat and add one-quarter teaspoon each of ground ginger and black pepper. You could also make this into golden milk by using coconut milk instead of water. Since curcumin is fat-soluble, consuming it with a fat-containing food or beverage helps you absorb it more effectively.
Look beyond the sweet taste of this powerful spice: Nutmeg, used unwisely, can poison you. It's been used over the centuries as a psychedelic, to stimulate menstruation and induce abortions, and to fight infections, including the Black Plague. Its popularity as a poor man's hallucinogen -- it takes only two tablespoons to have effects -- became legend when Malcolm X wrote about using it in prison.
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Mun, S. H., Kim, H. S., Kim, J. W., Ko, N. Y., Kim, do K., Lee, B. Y., Kim, B., Won, H. S., Shin, H. S., Han, J. W., Lee, H. Y., Kim, Y. M., and Choi, W. S. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. J Pharmacol Sci. 2009;111(1):13-21. View abstract.
Important note: No conclusive studies have been done on the effects of taking massive amounts of Forskolin in a short period of time in humans. There have also been no major studies with a solid understanding of how Forskolin will interact with the various medications listed. While most of the studies cited in this article didn’t note any major side effects, each person’s body is different and there are some possible interactions we do know about, such as the blood pressure issue. Nevertheless, one of the positive sides of Forskolin highlighted in some of the studies was that results were achieved without adverse effects.
If you’ve done even a little clicking around the wellness corner of the internet, you’ve likely encountered articles about turmeric and its awesomeness, but knowing how to actually fit it into your everyday life? Not always so obvious. While many studies focus on very concentrated preparations of curcumin in powder, tablet, or extract form intended for therapeutic dosing, eating turmeric as part of your day-to-day diet can be the best way to enjoy those benefits. Read on to learn more about how to use turmeric to boost your health and wellness.
A clinical study published in the journal Obesity discovered that Forskolin has a positive effect on the breakdown of stored fats without changing your diet or exercise routine by using the most important piece of the puzzle: 100% pure Coleus Forskohlii extract. The scientists of the study also used 500mg of Forskolin for their research. Not using the right type of Forskolin could prove to be a waste of your time and money. But what other factors are important?
Fiala, M., Liu, P. T., Espinosa-Jeffrey, A., Rosenthal, M. J., Bernard, G., Ringman, J. M., Sayre, J., Zhang, L., Zaghi, J., Dejbakhsh, S., Chiang, B., Hui, J., Mahanian, M., Baghaee, A., Hong, P., and Cashman, J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. Proc.Natl.Acad.Sci.U.S A 7-31-2007;104(31):12849-12854. View abstract.
Research studies are most often focused on the antioxidant and anti-inflammatory properties of turmeric’s main active ingredient curcumin (no relation to the spice cumin), which may offer protection against certain cancers, treat arthritis, benefit those with inflammatory bowel disease, reduce blood sugar, and help prevent Alzheimer’s disease. Turmeric has been recommended to support liver health, but some research suggests the potential for liver toxicity.
The remaining modifications of the core ring system A can putatively be understood as a series of oxidation reactions to form a poly-ol B which is then further oxidized and esterified to form the ketone and acetate ester moieties seen in forskolin. However, because the biosynthetic gene cluster has not been described, this putative synthesis could be incorrect in the sequence of oxidation/esterification events, which could occur in almost any order.
Since that breakthrough trial, at least two other studies have observed the impact of turmeric’s major compound, curcumin, in patients with depression. The first involved 56 individuals (male and female), and the second involved 108 male participants. Both used a placebo but did not compare curcumin to any antidepressant, and both studies found that curcumin effectively reduced depression symptoms more than placebo. (15, 16)
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Garcea, G., Berry, D. P., Jones, D. J., Singh, R., Dennison, A. R., Farmer, P. B., Sharma, R. A., Steward, W. P., and Gescher, A. J. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol.Biomarkers Prev. 2005;14(1):120-125. View abstract.
Turmeric paper, also called curcuma paper or in German literature, Curcumapapier, is paper steeped in a tincture of turmeric and allowed to dry. It is used in chemical analysis as an indicator for acidity and alkalinity. The paper is yellow in acidic and neutral solutions and turns brown to reddish-brown in alkaline solutions, with transition between pH of 7.4 and 9.2.
If you want to go to the max, you can think about minimizing total fructose consumption to <25g/day of added sugar; that’s the amount of added sugar in a single 8oz serving of Coke or fruit juice. Note: it is not so easy to detect fructose since “sugar” is used generically on food labeling. Sugar is a generic term on the food label. It is not what we call “sugar” which is technically called sucrose, a 50/50 mix of glucose/fructose. For example, the sugar is milk has no fructose, but it says “sugar” in the nutrition label. Table sugar is half glucose, half fructose, but it is also called “sugar” in the nutrition label. So best is to read more about this elsewhere as covering this is a topic in itself. Avoid sugar alcohols such as sorbitol, isomalt maltitol and mannitol since these break down to fructose. In general, “added sugar” is bad. Avoid all fruit juices like orange juice, Odwalla drinks, etc. Do yourself a favor and watch Lustig’s video on Fructose 2.0. It’s long, but it very important, he’s an entertaining speaker, and he’s right (e.g., see Peter Attia’s review of Lustig’s talk). Eating fructose in real foods such as fruit is fine since it has fiber which slows the rate of digestion so it hits the liver at a rate that the liver can process it properly.
Diet is #2. You must fix your diet or you’ll never lose your belly fat. Eat at no more than an average daily 25% deficit to your TDEE. If you are lean, you may want to use a 20% deficit; if you are overweight, you can use a higher deficit. I use the Fat Secret app to track my macros (because My Fitness Pal was always “updating” ever time I started the app). I can eat anything I want if I log it and it fits my caloric goal; this approach to flexible dieting is known as the IIFYM diet. I used to use My Fitness Pal but it was so annoying since it “updates” every time you bring up the app so I ditched it for Fat Secret which I’m very happy with. I also weigh all my food on a food scale. If you are serious about losing weight, you have only two choices: 1) stick to pre-calculated meals or 2) log your calories. If you under eat (like a 50% deficit) you will burn muscle and store fat. If you don’t restrict enough, you will not lose weight. So there is a very narrow range for losing fat. That’s why you need to track. My TDEE is 2500 calories so I shoot for 2000 calories/day for no longer than 2 weeks. Then I’m back at 2500 for the next 2 weeks. The two week on/off has been shown to be superior to a fixed deficit.
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Virtual gastric band uses hypnosis to make the brain think the stomach is smaller than it really is and hence lower the amount of food ingested. This brings as a consequence weight reduction. This method is complemented with psychological treatment for anxiety management and with hypnopedia. Research has been conducted into the use of hypnosis as a weight management alternative. In 1996 a study found that cognitive-behavioral therapy (CBT) was more effective for weight reduction if reinforced with hypnosis. Acceptance and Commitment Therapy ACT, a mindfulness approach to weight loss, has also in the last few years been demonstrating its usefulness.
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The curcumin group showed the highest percentage of improvement in overall [Disease Activity Score] scores and these scores were significantly better than the patients in the diclofenac sodium group. More importantly, curcumin treatment was found to be safe and did not relate with any adverse events. Our study provides the first evidence for the safety and superiority of curcumin treatment in patients with active RA, and highlights the need for future large-scale trials to validate these findings in patients with RA and other arthritic conditions.
The more you have to lose (obese / extremely overweight), the more you will lose as your body has more fat to spare. Sure, changes to your diet and activity levels will be the base but the magic lies in the details. Most people weight loss journey is mostly about losing a lot of water (and water weight), going on holiday and then coming back home feeling fat and full of guilt. The truth is, fat has nothing to do with it, because they haven’t lost much of it in the first place.