In 2009, Biochemistry and Biophysical Research Communications published a lab study out of Auburn University that explored the potential of curcuminoids to lower glucose levels. The study discovered that curcumin in turmeric is literally 400 times more potent than metformin (a common diabetes drug) in activating the enzyme AMPK (AMP-activated protein kinase). One compound produced by fermentation of curcumin, tetrahydrocurcumin, activated AMPK up to 100,000 times more than metformin in certain cells! (38)
I highly recommend using turmeric in recipes and perhaps even purchasing it in supplement form to take advantage of turmeric benefits. Make sure to add only organic turmeric to your food, and finding a high-quality turmeric supplement made from organic turmeric, coupled with black pepper and preferably prepared by fermentation. This way you can ensure you’re getting the best turmeric benefits possible.
It is often confusing! Often we find that people who want to get into a better shape are often very confident in how to lose the extra pounds. Yet, despite of visiting the gym, sweating hard and controlling a strict diet, many of them can’t address the stomach. This is a solid reminder that many of the ideas the fitness industry preaches are plain and simple, wrong.
The supplement is also named after the desired compound in this herb that achieves the fat-burning effects: forskolin (also called “coleonol”), a labdane diterpene unique to Indian Coleus only. Labdane diterpenes are found in many other plants, but what makes the ones from Indian Coleus so exciting is their unique, impressive effects: found in no other plant in the world. (1)
Dr. Oz is easy to impress. He cites a randomized placebo-controlled double blind trial of forskolin. It was a small preliminary study of obese or overweight men; there were only 15 men in each group, and the study lasted for 12 weeks. The subjects on forskolin showed favorable changes in body composition: a significant decrease in body fat percentage and fat mass, with a trend (non-significant) toward increased bone mass and lean body mass. Serum free testosterone levels were also significantly increased.
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According to Dariush Mozaffarian at Tufts, it’s not just excessive fructose, alcohol, trans fats, and BCAAs however. Both starch and sugars, in rapidly digested and high dose forms (aka the “refined carbs” as found in processed foods), are leading causes of NAFLD and metabolic syndrome. While fructose goes directly to de novo lipogenesis (DNL), glucose does as well when quickly digested in larger doses (starch or sugar)! So look at overall starch and sugar injestion, not fructose per se. A baked potato is essentially 100% glucose - avoid. Small amounts of potato mixed in with veggies, plant oils, etc. are better, but still best to just avoid - so many other fruits and nonstarchy veggies to eat. For carb-rich foods: 1) think of them as small sides, never the main part of the plate, and 2) look at the ratio of carb to fiber as a good general rule. Look for <10:1 ratio: no more than 10 g of total carb for every 1 g of fiber; the lower the better.
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Can we draw conclusions on meal timing based on small, short-term studies? It’s hard to know whether results like this would hold up over the long haul or with more diverse populations (say, older, less healthy people, people of different backgrounds, etc.). And there are practical issues, too. Our work schedules and family obligations may make it difficult to get your biggest meal in the morning and cut off eating in the evening hours.
If you get enough protein and fat, your total calorie intake should take care of itself. Because you feel full, you won't binge on a can of Pringles and blow your calorie count for the day. The remaining 45 percent of calories in our plan comes from carbohydrates — enough to give your palate a full range of tastes and your body a combination of fast- and slow-burning fuel.