Lee, H. Y., Kim S. W., Lee, G. H., Choi, M. K., Jung, H. W., Kim, Y. J., … & Chae, H. J. (2016, August 26) Turmeric extract and its active compound, curcumin, protect against chronic CCI4-induced liver damage by enhancing antioxidation. BMC Complementary and Alternative Medicine, 16(1), 316. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/27561811
As you can see, even if you aren’t trying to lose weight, adding a daily Forskolin supplement to your diet has other amazing benefits, and there are plenty of other studies to back them up, too. As far as weight loss goes though, the supplement is pretty powerful. The above benefits outline two additional ways that Forskolin may help you lose weight. If you experience hypothyroidism or are prediabetic, you may have a hard time losing weight. However, with Forskolin, you can combat these conditions, increasing your chances for weight loss. 

More recently, it’s played an important role in scientific research because of its ability to activate cAMP accumulation. (15) What does that mean, exactly? Well, cAMP (also known as cyclic adenosine monophosphate or cyclic amp) is a “second messenger” that impacts various biological processes. These second messengers are responsible for helping your cells understand how to process the messages of various “first messengers,” like epinephrine or serotonin. The first messengers begin cellular processes, and then second messengers act as translators in cellular processes within your body.

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Include physical activity in your daily routine. For most healthy adults, the Department of Health and Human Services recommends moderate aerobic activity, such as brisk walking, for at least 150 minutes a week or vigorous aerobic activity, such as jogging, for at least 75 minutes a week. If you use a step counter, remember that it takes an average of 10,000 steps per day to prevent weight gain. Some studies indicate it might take 15,000 steps per day to prevent the regain of weight after significant weight loss.
In the UK, up to 5% of the general population is underweight, but more than 10% of those with lung or gastrointestinal diseases and who have recently had surgery.[29] According to data in the UK using the Malnutrition Universal Screening Tool ('MUST'), which incorporates unintentional weight loss, more than 10% of the population over the age of 65 is at risk of malnutrition.[29] A high proportion (10-60%) of hospital patients are also at risk, along with a similar proportion in care homes.[29]
Arteries (are-te-rease): The blood vessels that carry oxygen-rich blood away from your heart for delivery to every part of your body. Arteries look like thin tubes or hoses. The walls are made of a tough outer layer, a middle layer of muscle and a smooth inner wall that helps blood flow easily. The muscle layer expands and contracts to help blood move.
A few months later, the second human study was completed, this time on 23 women. Again, these women received the same dosage for the same time period,as the first study. Unlike the first study, researchers found “no significant differences in fat mass or fat free mass,” meaning that body composition was not affected. In addition, no significant differences were found in any metabolic markers or blood lipids (such as increased testosterone found in the first study).
Forskolin is an extract derived from the roots of the Indian coleus (Coleus forskohlii), a tropical plant related to mint. Historically, coleus has been used in Indian Ayurvedic medicine for more than 3,000 years, and ancient Sanskrit writings indicate that it was used to help promote a healthy heart and lungs.2 Other traditional uses include treating digestive issues such as stomachache, nausea and intestinal spasm, as well as skin infections like ringworm.3
Fortunately, Turmeric Forskolin falls in this category. This supplement has been gaining a lot of attention in recent years. This supplement has gained the attention of scientists and doctors and is very popular among many people who are overweight and are looking for an effective way to slim down. Perhaps, what made Turmeric Forskolin so special is that it has something that you cannot find in other products of a similar nature. Turmeric Forskolin contains two of the most naturally effective plants for weight loss. These two plants are turmeric and mint.
If you want to lose weight safely, Stanford recommends working to improve your diet (making sure you’re eating lean protein, whole grains, veggies, and fruit) and working out at least 150 minutes each week. It's also important to regularly get a good night’s sleep, work to reduce your stress levels, and make sure none of the medication you’re currently taking can lead to weight gain.
Take diet breaks. This is important for resetting your metabolism. There have been too many studies where people cut a few hundred calories off their diet and find that they don’t lose any weight. This is because your body adapts to the lower intake. There was a great study where they found dieting for 2 weeks, then eating normally for 2 weeks (at maintenance) actually resulted in double the fat loss (per unit time dieting) than doing it without breaks. Surprisingly, dieting every other day (known as alternate day fasting (ADF)) is not as effective as the 2 week on/2 week off plan. Check this out: Boost weight loss by taking 2-week dieting breaks, says study

Adjusting Your Diet – Yes, you might have to start counting your calories. At least for a while. Pay attention to what you’re eating. Whole foods like fruits and vegetables will be your best friends. Choose lean meats, healthy fats (avocado, olive and coconut oil, nuts), and whole grains. Eat mostly plants and cut your portion sizes in half and you’ll be on your way!


Curcumin is primarily available in capsule form from commercial manufacturers. The most common regimen is one to three 500 mg capsules daily with or without food. Powdered turmeric root has traditionally been used for indigestion at dosages of 0.5 to 3 g/day. Dosages of 3 to 6 g/day have been investigated to protect against ulcers. Daily oral doses of curcumin 3,600 mg have been typically used in clinical trials, but dosages of curcumin up to 8 g/day have been used. Higher doses are associated with adverse GI effects.
The notion that abdominal obesity is the most dangerous kind isn't new. Back in the 1940s, the French physician Jean Vague observed that some obese patients had normal blood chemistry, while some moderately overweight patients showed serious abnormalities that predisposed them to heart disease or diabetes. Almost always, the latter patients carried their fat around their middles. And, almost always, they were men.
Because of the terrible and outdated advice dished out. There is so much maths, calories in v calories out and super hard workouts advice that a really simple process has become saturated with unproven advice. Most of it makes no sense or in the case of calorie reduction ‘seems right’’ but it doesn’t work! So to get rid of fat; it’s all down to understanding one thing.
Although using turmeric frequently in your cooking is a great way to take advantage of the spice (particularly with healthy fats and black pepper), turmeric only contains about three percent absorbable curcumin in the powdered form used in food. (69) Along with adding turmeric into your diet, you may also consider taking it or curcumin in supplement form — some high-quality turmeric supplements contain up to 95 percent curcuminoids.
Continuing weight loss may deteriorate into wasting, a vaguely defined condition called cachexia.[30] Cachexia differs from starvation in part because it involves a systemic inflammatory response.[30] It is associated with poorer outcomes.[25][30][31] In the advanced stages of progressive disease, metabolism can change so that they lose weight even when they are getting what is normally regarded as adequate nutrition and the body cannot compensate. This leads to a condition called anorexia cachexia syndrome (ACS) and additional nutrition or supplementation is unlikely to help.[27] Symptoms of weight loss from ACS include severe weight loss from muscle rather than body fat, loss of appetite and feeling full after eating small amounts, nausea, anemia, weakness and fatigue.[27]
Forskolin might decrease blood pressure. Taking forskolin with medication for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

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Doctors think that curcumin stays in the digestive system and is absorbed by the cells in the bowel. To find out more, a small study in the UK looked at how curcumin is absorbed from the human gut into liver cells. This study looked at how much of the curcumin is absorbed into both cancer cells and normal cells. This was a very small study of people with bowel cancer that had spread to the liver. They were given curcumin for 7 days before surgery. 

“If you are looking to speed up weight loss, adding 30 minutes of cardio three times per week will certainly help burn calories and body fat,” says Amie Hoff, Certified Fitness Professional in New York City. Short on time? Hoff suggests a HIIT (High Intensity Interval Training) workout. “The idea is to push your body hard for a short burst with a period of recovery. I like to have people start with a 10 to 15 second sprint (run, bike, jump rope, run stairs or anything that gets your heart rate up) and then back off for 30 seconds to recover. As you get stronger, you will increase the sprint time and decrease the recovery period. A 15 minute HIIT session can be equivalent to a regular 30 minute cardio workout.”

Tame your stress levels: I know it's easier said than done and I wince at even putting this on the list and making you feel like you're being lectured, but I've got to. There are a lot of things that we can't change in life, but we can adapt and handle them better. Carve out a little time for yourself in the day and try to fill it with something that you enjoy that you find relaxing. Yoga, stretching, writing, reading, meditating - whatever it is, try to treat yourself to at least a little something that settles your mind when you're feeling really stressed out. Stress can wreak havoc on health - not just on appearance or the storing of fat - and it should not be taken lightly.

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In today’s modern era of 24-hour meal delivery and extra-large food portions, many people are confused about how much and how often to eat. Gueron says one of the most common questions she gets is, “How late can I eat dinner and still lose weight?” Recently, several studies have shown that avoiding food past certain hours of the day or intermittent fasting can promote weight loss. She says a moderate approach that boosts weight loss and comes without apparent side effects for the healthy individual is the 12-hour intermittent fasting approach. An example is having your first morning meal no earlier than 7 a.m. and your last evening meal no later than 7 p.m. Thus, 12 hours without food or caloric beverages consumed gives your body time to rest from eating and promotes fat burning without unnecessary hunger that daytime fasting can cause.
Phytochemical components of turmeric include diarylheptanoids, a class including numerous curcuminoids, such as curcumin, demethoxycurcumin, and bisdemethoxycurcumin.[7] Curcumin constitutes up to 3.14% of assayed commercial samples of turmeric powder (the average was 1.51%); curry powder contains much less (an average of 0.29%).[18] Some 34 essential oils are present in turmeric, among which turmerone, germacrone, atlantone, and zingiberene are major constituents.[19][20][21]
"Refined grains like white bread, crackers, and chips, as well as refined sugars in sweetened drinks and desserts increase inflammation in our bodies," says Patton. "Belly fat is associated with inflammation, so eating too many processed foods will hinder your ability to lose belly fat." Natural foods like fruits, vegetables, and whole grains are full of antioxidants, which have anti-inflammatory properties and may therefore actually prevent belly fat, Patton says.

Garcinia Cambogia (GC) – Users have seen similar results when taking this supplement as with taking Forskolin. One user says she lost 25 pounds in two months on GC, which averages out to a weight loss of about three pounds a week. People using GC also report less food cravings, though you shouldn’t take Garcinia every day for a period longer than 12 weeks.

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Forskolin might slow blood clotting. Taking forskolin along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

"When going out for fast food, I used to get the large-size value meal. Now, I satisfy a craving by ordering just one item: a small order of fries or a six-piece box of chicken nuggets. So far, I've shaved off 16 pounds in seven weeks, and I'm on track to being thinner than my high school self for my 10-year reunion later this year." —Miranda Jarrell, Birmingham, AL
I highly recommend using turmeric in recipes and perhaps even purchasing it in supplement form to take advantage of turmeric benefits. Make sure to add only organic turmeric to your food, and finding a high-quality turmeric supplement made from organic turmeric, coupled with black pepper and preferably prepared by fermentation. This way you can ensure you’re getting the best turmeric benefits possible.

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Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue. Weight loss can either occur unintentionally due to malnourishment or an underlying disease or arise from a conscious effort to improve an actual or perceived overweight or obese state. "Unexplained" weight loss that is not caused by reduction in calorific intake or exercise is called cachexia and may be a symptom of a serious medical condition. Intentional weight loss is commonly referred to as slimming.

“If we break all of this down, here’s what we’re left with: Based on just 2 clinical studies performed on this chemical, forskolin may help improve your body composition and could potentially help prevent you from gaining weight, but there is zero clinical evidence showing that it can actually help you lose weight. This is a small, albeit extremely important, difference.”
Prostate cancer. Research suggests that taking a formula containing broccoli powder, turmeric powder, pomegranate whole fruit powder, and green tea extract three times daily for 6 months prevents an increase in prostate specific antigen (PSA) levels in men with prostate cancer. PSA levels are measured to monitor how well prostate cancer treatment is working. However, it's not yet known if this formula, or turmeric alone, reduces the risk of prostate cancer progression or recurrence.
Dr. Oz is a big supporter and spokesperson for Forskolin as a weight loss aid, and his reviews of the product certainly lend it some valuable credibility. To add to the authenticity of a supplement’s effects, Doctor Oz will often invite diet experts and guests on to his show who have taken the supplement, lost weight, and who also kept the weight off indefinitely!
Allergy protection. Forskolin’s properties that work to open airways, relieving asthma also improve pulmonary function that may be affected by allergies. In addition, there are studies that show that Forskolin may increase cAMP levels. Higher cAMP levels are associated with fewer allergy symptoms, and many medicines that are taken to combat allergies work to increase cAMP levels in the body.
Tame your stress levels: I know it's easier said than done and I wince at even putting this on the list and making you feel like you're being lectured, but I've got to. There are a lot of things that we can't change in life, but we can adapt and handle them better. Carve out a little time for yourself in the day and try to fill it with something that you enjoy that you find relaxing. Yoga, stretching, writing, reading, meditating - whatever it is, try to treat yourself to at least a little something that settles your mind when you're feeling really stressed out. Stress can wreak havoc on health - not just on appearance or the storing of fat - and it should not be taken lightly.

Mun, S. H., Kim, H. S., Kim, J. W., Ko, N. Y., Kim, do K., Lee, B. Y., Kim, B., Won, H. S., Shin, H. S., Han, J. W., Lee, H. Y., Kim, Y. M., and Choi, W. S. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. J Pharmacol Sci. 2009;111(1):13-21. View abstract.
*The products and the claims made about specific products on or through this site have not been evaluated by Divine Nutraceuticals of America or the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a health care professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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Take diet breaks. This is important for resetting your metabolism. There have been too many studies where people cut a few hundred calories off their diet and find that they don’t lose any weight. This is because your body adapts to the lower intake. There was a great study where they found dieting for 2 weeks, then eating normally for 2 weeks (at maintenance) actually resulted in double the fat loss (per unit time dieting) than doing it without breaks. Surprisingly, dieting every other day (known as alternate day fasting (ADF)) is not as effective as the 2 week on/2 week off plan. Check this out: Boost weight loss by taking 2-week dieting breaks, says study

It is very easy to gain weight than to lose it. In most cases, it is not that people don’t want to lose weight; they just haven’t found the right way to do it. In the United States and all over the world, many people struggle to lose weight, a good number of these people spend money on products that won’t work for them. In fact, deciding on the right weight loss supplement and technique to use to slim down your weight maybe one of the toughest decision you will ever make.
The rat study concluded that “both forskolin and rolipram stimulated lipolysis and inhibited body weight increase by increasing cAMP levels.” So, forskolin increases  levels of cAMP, or cyclic amp, which is a molecule that in elevated levels helps boost fat burning compounds. In layman’s terms, the scientists found that forskolin did prevent weight gain, even on a diet that caused rats in other diet groups to gain significant amounts of weight. This is in line with the second study, finding that supplementation may help manage weight gain.

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Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., and Dehghanzadeh, G. R. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr 2012;22(1):50-57. View abstract.

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It wasn't until TV's most famous doctor featured Forskolin in his show that it came into international prominence. Dr. Oz, the most famous doctor in the world today, was so impressed with the amount of scientific data on Forskolin that he touted the extract as "lightning in a bottle" for its unbelievable ability to zap fat tissues found in the belly.
Routinely squeaking by on five hours or less per night increases visceral fat levels, according to a 2010 Wake Forest University study. What’s more, after analyzing 28 different studies, UK researchers found that people who slept 5.5 hours or less per night ate an extra 385 calories the day after compared to those who snoozed for at least 7 to 12 hours. On top of that, they preferred to munch on fatty foods full of empty calories, like chips.
One of the users said, “Turmeric Forskolin was introduced to me by a friend of mine. She had used it and she said that it really helped her lose weight. As a student with a part time job, I did not have enough time to look after my health. I tried to make some recipes that I found on the Internet and I even got a gym subscription. However, this was all of no use since I did not have enough time to do all this.
Do not exceed recommended dose. Not intended for pregnant or nursing mothers or children under the age of 18. Individuals taking blood thinners, any other medications, or have any known medical conditions should consult a physician before using any herbal supplements. Discontinue use and consult your doctor if any adverse reactions occur. Not intended to treat obesity; consult a physician before beginning any weight loss program. KEEP OUT OF REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. KEEP BOTTLE CLOSED TIGHTLY AND STORE IN A COOL, DRY PLACE.
Another glaucoma-related question is whether or not forskolin can be effective in preventing retinal ganglion cell death, the final step into blindness for glaucoma patients. Forskolin alone had some effect, but researchers discovered that a multi-target approach including two additional natural supplements, homotaurine and L-carnosine, protected the health of the eye best when injected. This study has, so far, only been conducted on rat subjects. (13)

I find that weight loss supplements miss the entire point of nutrition. If you tell people that the way to cut fat is by popping a pill then this will only cure the symptom and not the problem. Surely, if you can just take a weight loss supplement then you will neglect to change your diet and lifestyle. The way to cut fat is to eat lots of fruit and vegetables, cut down on processed food and exercise. Anything else is lazy. Of course if you do all these things and still can’t lose weight then you need to see a doctor, not spend money on ‘miracle cures.’
When Johns Hopkins researchers compared the effects on the heart of losing weight through a low-carbohydrate diet versus a low-fat diet for six months—each containing the same amount of calories—those on a low-carb diet lost an average of 10 pounds more than those on a low-fat diet—28.9 pounds versus 18.7 pounds. An extra benefit of the low-carb diet is that it produced a higher quality of weight loss, Stewart says. With weight loss, fat is reduced, but there is also often a loss of lean tissue (muscle), which is not desirable. On both diets, there was a loss of about 2 to 3 pounds of good lean tissue along with the fat, which means that the fat loss percentage was much higher on the low-carb diet.
Do heavy compound weightlifting. 40 minute sessions done 3 times/week is sufficient. So a total of 2 hrs/week. This helps you preserve/build muscle mass during your cut. Starting Strength is an excellent intro to weightlifting. I also highly recommend Bigger, Leaner, Stronger. Those were the two books I relied upon to learn weightlifting and they will get you a long way. By weightlifting during your cut, you will be able to add muscle while losing fat if you are new to weightlifting as I was. During a cut (e.g., 500 calorie deficit), you’ll add muscle at a rate that is about 1/2 of what you’d add if you were in a (more efficient) lean bulking phase (5 to 10% calorie surplus). Experienced lifters like Jeff Cavaliere claim to be able to lose fat and gain muscle without a net caloric surplus by increasing your protein intake. Other experts such as Jordan Feigenbaum say you can’t do both (except if you are a newbie lifter).
My only worry is that it raises free testosterone. Many women today are having reproductive issues (mainly PCOS, which already raises free testosterone levels and causes a world of problems). I wonder if this would raise the number of PCOS cases or cause more issues in women with hormonal imbalances. I really look forward to seeing more studies in this because it is so difficult to lose weight with these issues.

Most detoxification of xenobiotics takes place within the liver in two phases: Phase I and Phase II. However, many people, particularly in the Western world, are so overexposed to these toxins that the liver is strained to the point of functioning at less-than-optimum levels. Several plant foods seem to aid the body in maintaining its natural detoxification rhythms and help the liver to operate correctly, and turmeric is one of the major players. Other common detoxifying plant foods include cruciferous vegetables (broccoli sprouts, kale, and many more), garlic, onions and citrus peel. (60)
One lab study observed the effects of forskolin on genetic material and found evidence of genotoxicity, the destruction of DNA that can potentially lead to mutations and cancer. (16) Taking forskolin may also cause rapid or irregular heartbeat in some people, so if you experience these symptoms while taking it, you should discontinue use and see your doctor immediately.
Curcumin is primarily available in capsule form from commercial manufacturers. The most common regimen is one to three 500 mg capsules daily with or without food. Powdered turmeric root has traditionally been used for indigestion at dosages of 0.5 to 3 g/day. Dosages of 3 to 6 g/day have been investigated to protect against ulcers. Daily oral doses of curcumin 3,600 mg have been typically used in clinical trials, but dosages of curcumin up to 8 g/day have been used. Higher doses are associated with adverse GI effects.
The upshot of all these chemicals floating around is big trouble for big-bellied guys. In a study at the University of Alabama at Birmingham, researchers took 137 men of all ages and sizes and used seven different measurements to determine their risks of cardiovascular disease. The single best sign of multiple heart-disease risks? No, it wasn't the guys' family histories or their cholesterol profiles. It was the amount of abdominal fat they carried.

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Sure, high-intensity cardio can help you torch calories, but ideally, you’ll also need to pump some iron to build metabolism-boosting muscle. That’s because strength training is one of the few activities you can do to spike the amount of calories you burn, even after you’re done with your workout. Case in point: one 2012 review of research found that while completing a 20-minute resistance training circuit may help you burn 200 calories, your body’s resting metabolic rate stays elevated for the next hour, helping you burn an additional 50 calories. Plus, when you lose weight, you lose some muscle with it, so building and maintaining that lean mass will help you achieve a more toned look.

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More recently, it’s played an important role in scientific research because of its ability to activate cAMP accumulation. (15) What does that mean, exactly? Well, cAMP (also known as cyclic adenosine monophosphate or cyclic amp) is a “second messenger” that impacts various biological processes. These second messengers are responsible for helping your cells understand how to process the messages of various “first messengers,” like epinephrine or serotonin. The first messengers begin cellular processes, and then second messengers act as translators in cellular processes within your body.
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