Forskolin activates protein phosphatase 2 (PP2A), an enzyme that causes rapid rates of cell division. A study in 2011 at the University of Madrid found that forskolin’s activation of the PP2A enzyme had anti-tumor effects on rectal cancer tumors, stopping their growth. The results of this study indicate that, depending on the type of rectal cancer a patient has, forskolin may have positive effects on slowing or stopping tumor growth. (5)
A 2014 study on glycemia and oxidative stress in rats looked at forskolin’s effectiveness on the two conditions. The study, published in the International Journal of Medical Sciences, indicated that regular administration of forskolin (over the course of eight weeks) decreased fasting blood glucose levels. (8) While this preliminary study shows that this supplement may help diabetic and prediabetic patients, more research must be done in order to prove its level of efficacy.
The more you have to lose (obese / extremely overweight), the more you will lose as your body has more fat to spare. Sure, changes to your diet and activity levels will be the base but the magic lies in the details. Most people weight loss journey is mostly about losing a lot of water (and water weight), going on holiday and then coming back home feeling fat and full of guilt. The truth is, fat has nothing to do with it, because they haven’t lost much of it in the first place.