What’s more, your body digests protein more slowly than carbs, so it keeps you feeling fuller longer and zaps your need to needlessly snack. “During weight loss, you want more protein—to prevent hunger, enhance satiety, and minimize muscle loss, as long as there’s some degree of physical activity,” Tom Rifai, MD, regional medical director of metabolic health and weight management for the Henry Ford Health System in Detroit told Prevention.
Forskolin was shown to elicit favorable changes in body composition by significantly decreasing body fat percentage (BF%) and fat mass (FM) as determined by DXA compared with the placebo group (p < or = 0.05). Additionally, forskolin administration resulted in a change in bone mass for the 12-week trial compared with the placebo group (p < or = 0.05). There was a trend toward a significant increase for lean body mass in the forskolin group compared with the placebo group (p = 0.097). Serum free testosterone levels were significantly increased in the forskolin group compared with the placebo group (p < or = 0.05). The actual change in serum total testosterone concentration was not significantly different among groups, but it increased 16.77 +/- 33.77% in the forskolin group compared with a decrease of 1.08 +/- 18.35% in the placebo group.
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Doctors commonly face the challenge of patients initially responding to chemotherapeutic drugs and then later developing resistance. Curcumin appears to re-sensitize these patients’ cancer cells to the drugs, although the exact mechanisms of curcumin’s chemo-sensitization remain ambiguous. Study author, Ajay Goel, PhD, director of gastrointestinal research and translational genomics and oncology at Baylor Scott & White Research Institute, stated: (37)
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.
Routinely squeaking by on five hours or less per night increases visceral fat levels, according to a 2010 Wake Forest University study. What’s more, after analyzing 28 different studies, UK researchers found that people who slept 5.5 hours or less per night ate an extra 385 calories the day after compared to those who snoozed for at least 7 to 12 hours. On top of that, they preferred to munch on fatty foods full of empty calories, like chips.
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Do NOT over do it. You cannot rush the process of fat loss. Don’t do more than 1 hr/day of weightlifting and no more than 3X/week and generally fewer than 50 reps per workout. Don’t do more than 3 hours of cardio per week. Don’t cut your calories by more than 25%. Do not fast for more than 18 hours. You may “think” you are going to get results faster, but it always works against you. Your body is really good at taking defensive measures when it thinks it is threatened and you can actually gain weight in a severe deficit. Take everything slow and steady. Ironically, the slow approach is the fastest way to get it done. Heard of “The biggest loser” TV show? By taking a fast approach to weight loss, they truly were the biggest losers in the end. Six years later, they’ve not only regained their weight, but now they have also perhaps permanently lost the ability to lose weight.
Gastrointestinal disorders are another common cause of unexplained weight loss – in fact they are the most common non-cancerous cause of idiopathic weight loss. Possible gastrointestinal etiologies of unexplained weight loss include: celiac disease, peptic ulcer disease, inflammatory bowel disease (crohn's disease and ulcerative colitis), pancreatitis, gastritis, diarrhea and many other GI conditions.
According to Dariush Mozaffarian at Tufts, it’s not just excessive fructose, alcohol, trans fats, and BCAAs however. Both starch and sugars, in rapidly digested and high dose forms (aka the “refined carbs” as found in processed foods), are leading causes of NAFLD and metabolic syndrome. While fructose goes directly to de novo lipogenesis (DNL), glucose does as well when quickly digested in larger doses (starch or sugar)! So look at overall starch and sugar injestion, not fructose per se. A baked potato is essentially 100% glucose - avoid. Small amounts of potato mixed in with veggies, plant oils, etc. are better, but still best to just avoid - so many other fruits and nonstarchy veggies to eat. For carb-rich foods: 1) think of them as small sides, never the main part of the plate, and 2) look at the ratio of carb to fiber as a good general rule. Look for <10:1 ratio: no more than 10 g of total carb for every 1 g of fiber; the lower the better.
An increase in fiber intake is also recommended for regulating bowel movements. Other methods of weight loss include use of drugs and supplements that decrease appetite, block fat absorption, or reduce stomach volume. Bariatric surgery may be indicated in cases of severe obesity. Two common bariatric surgical procedures are gastric bypass and gastric banding. Both can be effective at limiting the intake of food energy by reducing the size of the stomach, but as with any surgical procedure both come with their own risks that should be considered in consultation with a physician. Dietary supplements, though widely used, are not considered a healthy option for weight loss. Many are available, but very few are effective in the long term.
Favor “real” foods (unprocessed or minimally processed), e.g., eggs, orange, apple, oatmeal, etc. This works because engineered foods with equal amount of sugar and fat (like cheesecake, brownies, etc) cause people (and animals) to overeat (Note: there was an excellent BBC show on this research which showed sugar alone and fat alone didn’t trigger obesity; it was foods with equal amounts). Natural foods are generally one or the other, never both, so you never “crave” natural foods and eat them to excess. If you stay away from temptation, compliance becomes much easier.
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