I read one of the studies that you linked to and checked out a number of others briefly just to see what the scientific studies have to say. Normally, I would be really reticent to believe that any supplement could actually assist in losing weight. The thing that really shocked me was that the study I read WAS a double-blind test with a placebo, and it found that forskolin absolutely showed an increase in fat loss over those taking a placebo. Another awesome side effect that was carefully documented was an increase in lean body mass and bone density. http://www.ncbi.nlm.nih.gov/pubmed/16129715


Turmeric might slow blood clotting. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Allergy protection. Forskolin’s properties that work to open airways, relieving asthma also improve pulmonary function that may be affected by allergies. In addition, there are studies that show that Forskolin may increase cAMP levels. Higher cAMP levels are associated with fewer allergy symptoms, and many medicines that are taken to combat allergies work to increase cAMP levels in the body.
In 2008 between US$33 billion and $55 billion was spent annually in the US on weight-loss products and services, including medical procedures and pharmaceuticals, with weight-loss centers taking between 6 and 12 percent of total annual expenditure. Over $1.6 billion a year was spent on weight-loss supplements. About 70 percent of Americans' dieting attempts are of a self-help nature.[23][24]
You can improve the effectiveness of your weight training with this supplement regimen, taken with 8oz of water before and after fasted training: HMB (2g), creatine (2.5g), beta alanine (2g), and TMG (aka betaine anhydrous) (1g). The beta alanine will make you tingle for a short time, but that’s normal. BCAA’s while highly touted for fasted training are worthless for pretty much of anything. Use the HMB instead.
In 2009, Biochemistry and Biophysical Research Communications published a lab study out of Auburn University that explored the potential of curcuminoids to lower glucose levels. The study discovered that curcumin in turmeric is literally 400 times more potent than metformin (a common diabetes drug) in activating the enzyme AMPK (AMP-activated protein kinase). One compound produced by fermentation of curcumin, tetrahydrocurcumin, activated AMPK up to 100,000 times more than metformin in certain cells! (38)

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NYU Langone Medical Center approaches the topic on Forskolin in a different way than mentioned thus far. The article states that any medical benefits ascribed to Plectranthus barbatus (Coleus forskohlii) are likely derived from the Forskolin within it. They also go on to say that, while there is plenty of information on the health benefits Forskolin provides, the scientific evidence is weak, so you should not consider it a valuable source for treating any ailments.

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Forskolin supplements contain extracts of a plant from the mint family, Indian Coleus. It’s native to tropical regions around the world, and has been used in traditional folk medicine in those same regions for hundreds of years. Specifically, the extract has been a staple of Ayurdevic Medicine, one of the oldest holistic based medicines on the planet. As we discuss the many benefits of Forskolin, you’ll begin to understand why this extract is so popular in this holistic tradition from India. Today, the plant has advanced greatly from its traditional uses and is studied by researchers around the world to discover its secrets. Its scientific name, Coleus forskohlii, is where the supplement gets its commercial name.
Some research suggests that forskolin may aid in weight loss and muscle building. In one very small study, overweight and obese men took 250 milligrams of a 10% forskolin extract twice a day. After 12 weeks, they lost more body fat and had a greater increase in testosterone levels compared to similar men taking a placebo. But more research must be done to confirm these results and establish its safety.

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It’s natural for anyone trying to lose weight to want to lose it very quickly. But evidence shows that people who lose weight gradually and steadily (about 1 to 2 pounds per week) are more successful at keeping weight off. Healthy weight loss isn’t just about a “diet” or “program”. It’s about an ongoing lifestyle that includes long-term changes in daily eating and exercise habits.
While it might sound counterintuitive to eat something before you head out to a restaurant or party, showing up famished to the event will likely make it all the harder to stick to your weight loss goals. Eating something small (about 100 calories) with fiber (two to four grams) is a great way to readjust your appetite so you can show up and mingle a bit before diving into the cheese dip. Choose a whole food to take the edge off, like an apple or handful of nuts. For example, 30 pistachios are just 100 calories and offer two grams of fiber, along with protein and healthy fats, to truly take the edge off your appetite while providing a satisfying pre-party crunch. Enjoy your mini snack with a tall glass of water before the festivities to reduce your chances of post-party weight gain.
Jump up ^ Mann, T; Tomiyama, AJ; Westling, E; Lew, AM; Samuels, B; Chatman, J (April 2007). "Medicare's search for effective obesity treatments: diets are not the answer". The American Psychologist. 62 (3): 220–33. doi:10.1037/0003-066x.62.3.220. PMID 17469900. In sum, there is little support for the notion that diets ["severely restricting one’s calorie intake"] lead to lasting weight loss or health benefits.
Look beyond the sweet taste of this powerful spice: Nutmeg, used unwisely, can poison you. It's been used over the centuries as a psychedelic, to stimulate menstruation and induce abortions, and to fight infections, including the Black Plague. Its popularity as a poor man's hallucinogen -- it takes only two tablespoons to have effects -- became legend when Malcolm X wrote about using it in prison.

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Continuing weight loss may deteriorate into wasting, a vaguely defined condition called cachexia.[30] Cachexia differs from starvation in part because it involves a systemic inflammatory response.[30] It is associated with poorer outcomes.[25][30][31] In the advanced stages of progressive disease, metabolism can change so that they lose weight even when they are getting what is normally regarded as adequate nutrition and the body cannot compensate. This leads to a condition called anorexia cachexia syndrome (ACS) and additional nutrition or supplementation is unlikely to help.[27] Symptoms of weight loss from ACS include severe weight loss from muscle rather than body fat, loss of appetite and feeling full after eating small amounts, nausea, anemia, weakness and fatigue.[27]
If you exaggerate the amount, side effects such as dizziness, nausea, vomiting or diarrhea can be observed in mild cases and problems such as numbness in the body, yellowing of the skin or eyes and bleeding in more severe cases. However, there is nothing to worry about, since it is very difficult for anyone to eat 5 grams of saffron in a single day.

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